Low-Dose Glucagon to Prevent Exercise-Associated Hypoglycemia

A Systematic Review and Meta-analysis found that micro-dosing (100–300 μg) of glucagon increases blood glucose by ~1.5–2 mmol/L within 15 minutes, making it a viable alternative to “sugar loading” for unplanned exercise.

Takeaway: For T1Ds using AID systems (like Tandem or OmniPod), micro-dosing glucagon during intense lifting may prevent the “crash-spike” cycle that can happen with glucose tablets.

Read the full article (Diabetes Care, August 20, 2025)