Resistance Training Variables for Optimization of Muscle Hypertrophy: An Umbrella Review

An Umbrella Review (14 Meta-analyses) confirms that eccentric contractions (the lowering phase) are critical, and very slow repetitions (>10 seconds) actually hinder growth. Optimal volume is settled at ~10 sets/week per muscle.

Read the full article (Frontiers in Sports and Active Living, 2022; updated 2025)